Using single cell approaches to understand neointimal lesion formation and growth in Pulmonary Hypertension

Dec 05, 2022 (Mon) | 12:00 PM -1:00 PM
Zoom Link Below : Zoom, CA

The single cell approach to understand how arteries change in pulmonary arterial hypertension (PAH), a disease with by profound vascular remodeling. In PAH, pulmonary arteries narrow due to medial thickening and occlusion by neointimal lesions, which leads to elevated pulmonary vascular resistance and ultimately right heart failure. Therapies targeting the neointima would represent a significant advance in PAH treatment, and by understanding of the cellular events driving neointima formation, and the molecular pathways that control them, we hope to help develop new treatments. Using a wide array of approaches we are defining the cell behaviors underlying each stage of vascular remodeling, the progenitor populations that operate at each stage, and identifying the pathways that control them

Department:  Stanford Maternal and Child Health Research Institute

Contact: Neta Miller | 4083341776 | mneta@stanford.edu

Presenter(s):

  • Lea Steffes, MD Instructor
  • Maya Kumar, MD

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