Modeling familial and acquired cardiomyopathies using next generation human based models

Apr 26, 2021 (Mon) | 12:00 PM -1:00 PM
Zoom Meeting : Stanford, CA

In this presentation, Dr. Stillitano will show that human in vitro models, such as induced pluripotent stem cells derived cardiomyocytes (iPSC-CMs), and “humanized” mice represent reliable experimental models to investigate molecular mechanisms underlying inherited arrhythmogenic cardiomyopathy and to test the therapeutic potential of genome editing and gene therapy approaches. Dr. Stillitano will also show the potential of using a genetically diverse panel of subject-specific iPSC-CMs to model complex and acquired phenotypes, such as susceptibility to develop cardiotoxic drug response. This lecture is free and open to the public.

Department:  Spectrum: Center for Translational and Clinical Research and Education

Contact: Jessica P. Meyer | 6504986140 | jpmeyer@stanford.edu

Presenter(s):

  • Francesca Stillitano, PhD Assistant Professor, Medicine- Cardiology, Mt. Sinai

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